Pharmaceutical approach for pre mature

Try out PMC Labs and tell us what you think. Learn More. Premature ejaculation PE is a common male sexual dysfunction. Once the diagnosis of PE is established through a thorough history, a variety of medical therapies is available, including tricyclic antidepressants, selective serotonin reuptake inhibitors SSRIs , centrally acting opiates, phosphodiesterase 5 inhibitors and topical desensitizing creams. Most of these treatments increase the intravaginal ejaculation latency time IELT and patient satisfaction scores, with the most convincing evidence for SSRIs and topical creams. Daily SSRIs such as paroxetine, although efficacious, do have a substantial and prolonged side effect profile.

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Premature ejaculation: A clinical review for the general physician

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Medical therapy for premature ejaculation

Articles in the December issue discuss various health issues affecting school-aged children, including acne, eczema and growth disorders. Volume 44, No. Premature ejaculation is one of the most common sexual dysfunctions in men. This article will discuss the current definition of premature ejaculation from a urological perspective.
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Medical therapy for premature ejaculation

In addition to asking about your sex life, your doctor will ask about your health history and might do a physical exam. If you have both premature ejaculation and trouble getting or maintaining an erection, your doctor might order blood tests to check your male hormone testosterone levels or other tests. In some cases, your doctor might suggest that you go to a urologist or a mental health professional who specializes in sexual dysfunction. Common treatment options for premature ejaculation include behavioral techniques, topical anesthetics, medications and counseling.
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A Pubmed search from the year to the present was performed to retrieve publications related to management or treatment of premature ejaculation. Behavioral techniques have been the mainstay of premature ejaculation management for many years, although evidence of their short-term efficacy is limited. Topical therapies for premature ejaculation act by desensitizing the penis and do not alter the sensation of ejaculation. Selective serotonin reuptake inhibitors SSRIs , commonly used in the treatment of depression, are often used to treat premature ejaculation, based on the observation that delayed ejaculation is a frequent side effect of this drug class. Dapoxetine is a short-acting SSRI formulated to treat premature ejaculation, and results seem very promising.
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